Matic.JS/ how to call erc721 methods with matic.js

So I’m a young developer, who is looking to build an erc721 project. Matic is a no-brainer choice to build on. With that, I am ready to deploy on Mumbai testnet with truffle, after reading the docs. However, I am confused by the use of Matic.js library, as I will be using it in my backend Nodejs api for my dapp.

Shall/can I just use Web3.js to call my contract as I am more comfortable with it?